Vernakalant Hydrochloride [748810-28-8]

MedChem Express

Vernakalant Hydrochloride [748810-28-8]

10

748810-28-8

Research Use Only

95%

C20H32ClNO4

385.93

Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35+/-0.93 microM, 0.61+/-0.03 microM, and 1.63+/-0.09 microM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.

COC1=C(OC)C=C(CCO[C@H]2[C@H](N3CC[C@@H](O)C3)CCCC2)C=C1.Cl

2°C to 8°C,-20°C,-80°C

12352200