Vismodegib [879085-55-9]

MedChem Express

Vismodegib [879085-55-9]

10

879085-55-9

Research Use Only

95.22%

C19H14Cl2N2O3S

421.3

Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 microM and 1.4 microM, respectively.

O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl

2°C to 8°C,-20°C,-80°C

12352200