VS-5584 [1246560-33-7]

MedChem Express

VS-5584 [1246560-33-7]

10

1246560-33-7

Research Use Only

95%

C17H22N8O

354.41

VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC50s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1.

NC1=NC=C(C2=C3N=C(C)N(C(C)C)C3=NC(N4CCOCC4)=N2)C=N1

2°C to 8°C,-20°C,-80°C

12352200