VU0467154 [1451993-15-9]

MedChem Express

VU0467154 [1451993-15-9]

10

1451993-15-9

98%

C17H15F3N4O3S2

444.45

VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR), potentiating the response to ACh with pEC50s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively.

O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3

2°C to 8°C,-20°C,-80°C

12352200