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WIKI4 [838818-26-1]

Research Use Only
HY-16910
MedChem Express
CAS Number838818-26-1
Product group Chemicals
Estimated Purity99.51%
Molecular Weight521.59
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    WIKI4 [838818-26-1]
  • Delivery Days Customer
    10
  • CAS Number
    838818-26-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.51%
  • Molecular Formula
    C29H23N5O3S
  • Molecular Weight
    521.59
  • Scientific Description
    WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/beta-catenin signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on Wnt/beta-catenin signaling by inhibiting the enzymatic activity of TNKS2. WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02 microM.
  • SMILES
    O=C1N(CCCSC2=NN=C(C3=CC=NC=C3)N2C4=CC=C(OC)C=C4)C(C5=CC=CC6=CC=CC1=C56)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200