Wortmannin [19545-26-7]

MedChem Express

Wortmannin [19545-26-7]

10

19545-26-7

Research Use Only

98%

C23H24O8

428.43

Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC50s of 5.8 and 48 nM, respectively.

O=C1C([C@@](CC2)([H])[C@@]3(C)C2=O)=C([C@H](OC(C)=O)C3)[C@]4(C)C5=C1OC=C5C(O[C@@H]4COC)=O

2°C to 8°C,-20°C,-80°C

12352200