XAV-939 [284028-89-3]

MedChem Express

XAV-939 [284028-89-3]

10

284028-89-3

Research Use Only

95%

C14H11F3N2OS

312.31

XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation.

O=C1C(CSCC2)=C2N=C(C3=CC=C(C(F)(F)F)C=C3)N1

2°C to 8°C,-20°C,-80°C

12352200