Zardaverine [101975-10-4]

MedChem Express

Zardaverine [101975-10-4]

10

101975-10-4

98.16%

C12H10F2N2O3

268.22

Zardaverine is an orally active and selective PDE3/4 inhibitor (IC50)=0.58 uM/0.17 uM) with potent bronchodilator activity. Zardaverine also selectively inhibits the proliferation of HCC cells and induces apoptosis and cycle arrest (G0/G1 phase). Zardaverine has good antitumor potential and is effective in both bronchial relaxation and reduction of inflammation in asthma.

O=C1C=CC(C2=CC=C(OC(F)F)C(OC)=C2)=NN1

2°C to 8°C,-20°C,-80°C

12352200