Zatebradine [85175-67-3]

MedChem Express

Zatebradine [85175-67-3]

10

85175-67-3

Research Use Only

99.59%

C26H36N2O5

456.57

Zatebradine (UL-FS-49 (free base); UL-FS-49CL (free base)) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC50 value of 1.96 microM. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1.83 microM, 2.21 microM, 1.90 microM and 1.88 microM, respectively.

O=C1N(CCCN(CCC2=CC=C(OC)C(OC)=C2)C)CCC3=CC(OC)=C(OC)C=C3C1

2°C to 8°C,-20°C,-80°C

12352200