Nitazoxanide [55981-09-4]

Catalog number: HY-B0217_100mg
Brand: MedChem Express
Packing: 100 mg
Other sizes: 10 mg
10 mM
50 mg
Price: € 316.00
Expected delivery time: 10 days
Quantity:

Product specifications for - Nitazoxanide [55981-09-4]

Overview: 
Product group: Corona Related Products
Category: Other
CAS No.: 55981-09-4
Properties: 
Purity: >98%
Molecular Formula: C12H9N3O5S
Molecular weight: 307.28
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Scientific information: 
Scientific info: Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 uM). Target: Others Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. In vitro studies demonstrated much broader activity. Dr. Rossignol co-founded Romark Laboratories, with the goal of bringing nitazoxanide to market as an anti-parasitic drug. Initial studies in the USA were conducted in collaboration with Unimed Pharmaceuticals, Inc. (Marietta, GA) and focused on development of the drug for treatment of cryptosporidiosis in AIDS. The anti-protozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic energy metabolism. It has also been shown to have activity against influenza A virus in vitro. The mechanism appears to be by selectively blocking the maturation of the viral hemagglutinin at a stage preceding resistance to endoglycosidase H digestion. This impairs hemagglutinin intracellular trafficking and insertion of the protein into the host plasma membrane.
Safety information: 
MSDS: MSDS