MBS1230175-EColi | Recombinant Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein

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Product specifications for - Recombinant Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein

Overview:
Product group:	Corona Related Products
Category:	Proteins
Subcategory:	Recombinant protein
Target:	S
Target description:	spike surface glycoprotein

Properties:
Purity:	Greater than 90% as determined by SDS-PAGE.
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352202
Storage instructions:	-20-¦C or -80-¦C

Scientific information:
Scientific info:	S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Gene ID:	2648208
Swiss prot ID:	P36334

Additional information:
Synonyms:	E2; HCoVOC43gp4; Peplomer protein; S protein; spike surface glycoprotein

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Recombinant Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein

Product specifications for - Recombinant Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein