Recombinant Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein

Catalog number: MBS1230175_0,01mg
Brand: MyBioSource
Packing: 0,01 mg
Other sizes: Other sizes available, please contact us.
Price: On Request
Expected delivery time: 21 days

Product specifications for - Recombinant Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein

Product group: Corona Related Products
Category: Bacterial / viral proteins
Source: Human
Purity: Greater than 90% as determined by SDS-PAGE.
Molecular weight: 53,6 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: Liquid containing glycerol
Storage instructions: Store at -20-¦C , for extended storage, conserve at -20-¦C or -80-¦C.
Scientific information: 
Scientific info: S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Gene ID: 2648208
Swiss prot ID: P36334