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Remdesivir [1809249-37-3]
Catalog number:
HY-104077_100mg
Brand:
MedChem Express
Packing:
100 mg
Price:
On Request
Expected delivery time:
7 days
Quantity:
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References
Remdesivir Chemical Structure
CAS No. : 1809249-37-3...
Remdesivir Chemical Structure
CAS No. : 1809249-37-3
Product specifications for - Remdesivir [1809249-37-3]
Overview:
Product group:
Corona Related Products
Category:
Other
CAS No.:
1809249-37-3
Properties:
Purity:
>98%
Molecular Formula:
C27H35N6O8P
Molecular weight:
602.58
Datasheet:
Datasheet
Research Use Only
UNSPSC:
41116133
Scientific information:
Scientific info:
Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.
Safety information:
MSDS:
MSDS
Additional information:
Synonyms:
HY-104077; GS-5734; MedChem Express
Thi nhu thao T, Labroussaa F, Ebert N, et al. Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature. 2020;582(7813):561-565.
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Yin W, Mao C, Luan X, et al. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science. 2020;368(6498):1499-1504.
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Yuan S, Chan CC, Chik KK, et al. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020;12(6)
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Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020;30(3):269-271.
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Parang K, El-sayed NS, Kazeminy AJ, Tiwari RK. Comparative Antiviral Activity of Remdesivir and Anti-HIV Nucleoside Analogs Against Human Coronavirus 229E (HCoV-229E). Molecules. 2020;25(10)
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Vanden eynde JJ. COVID-19: A Brief Overview of the Discovery Clinical Trial. Pharmaceuticals (Basel). 2020;13(4)
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