Remdesivir [1809249-37-3]

Catalog number: HY-104077_100mg
Brand: MedChem Express
Packing: 100 mg
Price: On Request
Expected delivery time: 7 days
Remdesivir Chemical Structure
CAS No. : 1809249-37-3...

Product specifications for - Remdesivir [1809249-37-3]

Product group: Corona Related Products
Category: Other
CAS No.: 1809249-37-3
Purity: >98%
Molecular Formula: C27H35N6O8P
Molecular weight: 602.58
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116133
Scientific information: 
Scientific info: Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.
Safety information: 
Additional information: 
Synonyms: HY-104077; GS-5734; MedChem Express
Thi nhu thao T, Labroussaa F, Ebert N, et al. Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature. 2020;582(7813):561-565. Read more
Yin W, Mao C, Luan X, et al. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science. 2020;368(6498):1499-1504. Read more
Yuan S, Chan CC, Chik KK, et al. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020;12(6) Read more
Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020;30(3):269-271. Read more
Parang K, El-sayed NS, Kazeminy AJ, Tiwari RK. Comparative Antiviral Activity of Remdesivir and Anti-HIV Nucleoside Analogs Against Human Coronavirus 229E (HCoV-229E). Molecules. 2020;25(10) Read more
Vanden eynde JJ. COVID-19: A Brief Overview of the Discovery Clinical Trial. Pharmaceuticals (Basel). 2020;13(4) Read more