BPS Bioscience

BPS Bioscience is a leading developer and manufacturer for recombinant proteins, cell lines, assay kits and screening & profiling services. They supply, among others, kinases, phosphodiesterases, phosphatases, histone demethylases, histone methyltransferases, HDACs, and poly ADP ribose polymerases.

Today, BPS offers one of the largest selections of recombinant enzymes for drug discovery and continues to expand its drug discovery products. They also provides custom protein expression, biochemical and cell-based assays, and compound screening services.

BPS is customer-oriented, which means they listen to your needs and adapt their services to your situation. By being at the forefront of technology development. They focus on providing quality life science products and services in a timely manner that will help our customers to accelerate drug discovery and development for treatment of human diseases.

BPS Bioscience has always had high quality products and services and from November 2021 they are also ISO 9001 certified.

Bio-Connect Life Sciences supplies all their products in the Benelux. If you have any questions, please contact the helpdesk.

Major product lines from BPS Bioscience

• Proteins
• Biochemical assay kits
• Cell lines & primary cells
• Cell media & luciferase reagents
• Antibodies
• Inhibitors and activators
• Cell isolation kits
• Virus-based tools
• Cell-based assay expression kits

Innovating the future of drug discovery

Proteins, cell lines and assay kits

Ebooks by BPS Bioscience

BPS has released a couple of ebooks in collaboration with Biocompare. The first was called “Advances in Virology Research” and BPS contributed the following article: Lentivirus-based SARS-CoV-2 virus particles for the study of COVID-19. This ebook discusses tools and techniques to study SARS-CoV-2, including mechanisms of viral entry, viral structure, receptor binding, and the host immune response.

The second ebook was “Optimizing Gene-Editing Workflows”. This ebook discusses the techniques and challenges of using CRISPR/Cas9 technology for gene editing, including the difference between pooled and arrayed CRISPR screens and the advantages of each.

Publications with products by BPS Bioscience

• Banerjee N, Wang H, Wang G, Boor PJ, Khan MF. Differential expression of mirnas in trichloroethene-mediated inflammatory/autoimmune response and its modulation by sulforaphane: delineating the role of mirna-21 and mirna-690. Front Immunol. 2022;13:868539.
• Petrou A, Zagaliotis P, Theodoroula NF, et al. Thiazole/thiadiazole/benzothiazole based thiazolidin-4-one derivatives as potential inhibitors of main protease of sars-cov-2. Molecules. 2022;27(7):2180.
• Yu J, Gou W, Shang H, et al. Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors. J Enzyme Inhib Med Chem. 2022;37(1):952-972.
• Manry D, Bolanos K, DiAndreth B, Mock JY, Kamb A. Robust in vitro pharmacology of tmod, a synthetic dual-signal integrator for cancer cell therapy. Front Immunol. 2022;13:826747.
• Tsai MS, Shih WT, Yang YH, et al. Potential inhibitor for blocking binding between ACE2 and SARS-CoV-2 spike protein with mutations. Biomed Pharmacother. 2022;149:112802.
• Guan Y, Hasipek M, Jiang D, et al. Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia. J Clin Invest. 2022;132(4):e149856.
• Wang R, Wang Y, Liao G, et al. Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling. iScience. 2022;25(2):103833.
• Tokatlian T, Asuelime GE, Mock JY, et al. Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells. J Immunother Cancer. 2022;10(1):e003826.
• Basu A, Penumutchu S, Nguyen K, et al. A structurally conserved rna element within sars-cov-2 orf1a rna and s mrna regulates translation in response to viral s protein-induced signaling in human lung cells. J Virol. 2022;96(2):e0167821.
• El-Shennawy L, Hoffmann AD, Dashzeveg NK, et al. Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nat Commun. 2022;13(1):405.