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BMS-1166 [1818314-88-3]

Research Use Only
HY-102011
MedChem Express
CAS Number1818314-88-3
Product group Chemicals
Estimated Purity98.37%
Molecular Weight641.11
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMS-1166 [1818314-88-3]
  • Delivery Days Customer
    10
  • CAS Number
    1818314-88-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.37%
  • Molecular Formula
    C36H33ClN2O7
  • Molecular Weight
    641.11
  • Scientific Description
    BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
  • SMILES
    O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200