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IWP-O1 [2074607-48-8]

Research Use Only
HY-100853
MedChem Express
CAS Number2074607-48-8
Product group Chemicals
Estimated Purity99.61%
Molecular Weight432.48
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IWP-O1 [2074607-48-8]
  • Delivery Days Customer
    10
  • CAS Number
    2074607-48-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.61%
  • Molecular Formula
    C26H20N6O
  • Molecular Weight
    432.48
  • Scientific Description
    IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
  • SMILES
    O=C(CN1N=NC(C2=CC=NC=C2)=C1C3=CC=CC=C3)NC4=NC=C(C5=CC=CC=C5)C=C4
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200