Nevanimibe hydrochloride [133825-81-7]
HY-100399A
CAS Number133825-81-7
Product group Chemicals
Estimated Purity98.07%
Molecular Weight458.08
Overview
- SupplierMedChem Express
- Product NameNevanimibe hydrochloride [133825-81-7]
- Delivery Days Customer10
- CAS Number133825-81-7
- Estimated Purity98.07%
- Molecular FormulaC27H40ClN3O
- Molecular Weight458.08
- Scientific DescriptionNevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer.
- SMILESO=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200