SPHINX31 [1818389-84-2]

MedChem Express

SPHINX31 [1818389-84-2]

10

1818389-84-2

99.12%

C27H24F3N5O2

507.51

SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease.

O=C(NC1=C(N2CCN(CC3=CC=CC=N3)CC2)C=CC(C(F)(F)F)=C1)C4=CC=C(O4)C5=CC=NC=C5

2°C to 8°C,-20°C,-80°C

12352200