Zamicastat [1080028-80-3]
HY-106004
CAS Number1080028-80-3
Product group Chemicals
Estimated Purity95.36%
Molecular Weight401.47
Overview
- SupplierMedChem Express
- Product NameZamicastat [1080028-80-3]
- Delivery Days Customer10
- CAS Number1080028-80-3
- CertificationResearch Use Only
- Estimated Purity95.36%
- Molecular FormulaC21H21F2N3OS
- Molecular Weight401.47
- Scientific DescriptionZamicastat (BIA 5-1058) is a dopamine beta-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 microM and 17.0 microM, respectively. Zamicastat reduces high blood pressure.
- SMILESS=C1N([C@@H]2CC3=CC(F)=CC(F)=C3OC2)C(CCNCC4=CC=CC=C4)=CN1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200