Adeno-associated virus (AAV) is a small, non-enveloped virus composed of an icosahedral capsid that encloses a short, single-stranded DNA genome flanked by two ITR (inverted terminal repeats). AAVs are replication-defective, do not normally integrate into the host genome, and are non-pathogenic, and have become widely used tools for gene delivery in the treatment of genetic … Continue reading AAVs: toolbox for research on next-generation gene therapies