How ICL Outperforms USP’s Analytical Reference Standard Background on PLBL2 Host Cell Proteins in Biopharmaceutical Manufacturing Host Cell Proteins (HCPs) remain one of the most persistent challenges in biopharmaceutical manufacturing. Among them, phospholipase B-like 2 (PLBL2) from CHO cells is notorious for co-purifying with monoclonal antibodies and triggering immunogenic responses. A recent study published by … Continue reading ICL’s PLBL2 Reference Standard: Superior to USP Standards