ACE2 peptide (169-183)

Catalog number: GTX15354
Brand: GeneTex
Packing: 50 ug
Price: € 200.00
Expected delivery time: 10 days

Product specifications for - ACE2 peptide (169-183)

Product group: Proteins / Signaling Molecule
Category: Peptides
Application: Neutralisation/Blocking
Target: ACE2
Target description: angiotensin I converting enzyme 2
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352209
Concentration: 0.20 mg/ml
Storage instructions: Store the peptide at -20°C, stable for one year.
Scientific information: 
Scientific info: Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
Gene ID: 59272
Additional information: 
Synonyms: ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; angiotensin-converting enzyme homolog; metalloprotease MPROT15; peptidyl-dipeptidase A