AITRL/TNFSF18 Protein, Mouse
HY-P7319
Overview
- SupplierMedChem Express
- Product NameAITRL/TNFSF18 Protein, Mouse
- Delivery Days Customer10
- Protein IDQ7TS55
- Protein NameTumor necrosis factor ligand superfamily member 18
- Scientific DescriptionAITRL, a type II transmembrane protein, is a ligand for glucocorticoid-induced TNFR-related protein (GITR). When AITRL binds to GITR, GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor, inflammation, as well as autoimmune diseases. Besides, AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1). AITRL/TNFSF18 Protein, Mouse is a recombinant mouse AITRL (T47-S173) without tag, which is expressed in E.coli.
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202