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Angiotensin II human [4474-91-3]

HY-13948
MedChem Express
CAS Number4474-91-3
Product group Chemicals
Estimated Purity98.3%
Molecular Weight1046.18
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Angiotensin II human [4474-91-3]
  • Delivery Days Customer
    10
  • CAS Number
    4474-91-3
  • Estimated Purity
    98.3%
  • Molecular Formula
    C50H71N13O12
  • Molecular Weight
    1046.18
  • Scientific Description
    Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.
  • SMILES
    O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200