B7-H5 [VISTA] (human) (rec.) (His)

Catalog number: CHI-HF-201B7H5-C050
Brand: Chimerigen Laboratories
Packing: 50 ug
Price: € 320.00
Expected delivery time: 7 days
Quantity:

Product specifications for - B7-H5 [VISTA] (human) (rec.) (His)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Subcategory: Recombinant protein
Source: HEK 293 cells
Properties: 
Purity: >95% (SDS-PAGE)
Molecular weight: 32 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: Platelet receptor Gi24 (also known as Dies1, SISP1 and C10orf54) is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESCs, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Human Gi24 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Swiss prot ID: AAH20568.1
Additional information: 
Synonyms: CHI-HF-201B7H5-C050; Chimerigen Laboratories