BAY-545 [1699717-32-2]

MedChem Express

BAY-545 [1699717-32-2]

10

1699717-32-2

Research Use Only

95.88%

C18H22F3N3O4S

433.45

BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor.

CCN1C(N(CCC(F)(F)F)C2=C(C(C)=C(C(N3CCC(O)CC3)=O)S2)C1=O)=O

2°C to 8°C,-20°C,-80°C

12352200