CD137 (mouse):Fc (human) (rec.)

Catalog number: AG-40A-0025-C050
Brand: AdipoGen Life Sciences
Packing: 50 ug
Price: € 290.00
Expected delivery time: 7 days
Quantity:

Product specifications for - CD137 (mouse):Fc (human) (rec.)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Species: Mouse
Target: Tnfrsf9
Target description: tumor necrosis factor receptor superfamily, member 9
Source: 293 Cells
Properties: 
Purity: >95% (SDS-PAGE)
Molecular weight: ~50kDa (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 1 mg/ml
Form supplied: Liquid. 0.2um filtered solution in PBS.
Scientific information: 
Scientific info: CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice. - Protein. The extracellular domain of mouse CD137 (aa 1-185) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Liquid. 0.2microm filtered solution in PBS. Purity: >95% (SDS-PAGE). CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
Gene ID: 21942
Swiss prot ID: P20334
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; ILA; Ly63; secreted CD137 antigen; T-cell antigen 4-1BB; tumor necrosis factor receptor superfamily member 9