CD275 [B7-H2] (human):Fc (mouse) (rec.)

Catalog number: CHI-HF-211B7H2-C100
Brand: Chimerigen Laboratories
Packing: 100 ug
Price: € 350.00
Expected delivery time: 7 days

Product specifications for - CD275 [B7-H2] (human):Fc (mouse) (rec.)

Product group: Proteins / Signaling Molecule
Category: Proteins
Subcategory: Recombinant protein
Source: CHO cells
Purity: >98% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Swiss prot ID: NP_056074.1
Additional information: 
Synonyms: CHI-HF-211B7H2-C100; Chimerigen Laboratories; ICOSL / B7-H2; ICOSLG; LICOS; ICOSL; ICOS-L; GL50; CD275; B7RP1; B7RP-1; B7H2; B7-H2; transmembrane protein B7-H2 ICOS ligand; ICOS ligand; B7-related protein 1; B7-like protein Gl50; B7 homologue 2; B7 homolog 2; inducible T-cell co-stimulator ligand