CD278 [ICOS] (human):Fc (human) (rec.) (non-lytic)

Catalog number: CHI-HF-220ICOS-C100
Brand: Chimerigen Laboratories
Packing: 100 ug
Other sizes: 25 ug
Price: € 350.00
Expected delivery time: 7 days

Product specifications for - CD278 [ICOS] (human):Fc (human) (rec.) (non-lytic)

Product group: Proteins / Signaling Molecule
Category: Proteins
Subcategory: Recombinant protein
Source: CHO cells
Purity: >98% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Swiss prot ID: NP_036224.1
Additional information: 
Synonyms: CHI-HF-220ICOS-C100; Chimerigen Laboratories; ICOS; CVID1; CD278; AILIM; inducible costimulator; inducible T-cell costimulator; activation-inducible lymphocyte immunomediatory molecule; inducible T-cell co-stimulator