CD279 [PD-1] (human)-muIg Fusion Protein (preservative free)

Ancell Corporation

CD279 [PD-1] (human)-muIg Fusion Protein (preservative free)

10

Research Use Only

>95%

Human CD279 (PD-1; Programmed Cell Death 1) is a 55 kD Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses. - Protein. Liquid. 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. Human CD279 (PD-1; Programmed Cell Death 1) is a 55 kD Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses.

2°C to 8°C

12352202