CD40 (human):Fc (human) (rec.)

Catalog number: AG-40B-0083-C050
Brand: AdipoGen Life Sciences
Packing: 50 ug
Other sizes: 3 x 50 ug
Price: € 250.00
Expected delivery time: 7 days

Product specifications for - CD40 (human):Fc (human) (rec.)

Product group: Proteins / Signaling Molecule
Category: Proteins
Subcategory: Recombinant protein
Source: HEK 293 cells
Purity: >95% (SDS-PAGE)
Molecular weight: 54 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 1mg/ml after reconstitution.
Form supplied: Lyophilized. Contains PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Swiss prot ID: P25942
Safety information: 
Additional information: 
Synonyms: AG-40B-0083-C050; AdipoGen Life Sciences; Tumor Necrosis Factor Receptor Superfamily Member 5; TNFRSF5; CD40L Receptor