CD54 [ICAM-1] (mouse):Fc (mouse) (rec.) (non-lytic)

Catalog number: CHI-MF-120ICAM1-C050
Brand: Chimerigen Laboratories
Packing: 50 ug
Price: € 210.00
Expected delivery time: 7 days
Quantity:

Product specifications for - CD54 [ICAM-1] (mouse):Fc (mouse) (rec.) (non-lytic)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Species: Mouse
Properties: 
Purity: >98% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions: 2-¦C to 8-¦C, -20-¦C
Scientific information: 
Scientific info: Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation. - Protein. The extracellular domain of mouse CD54 [ICAM-1] (aa 28-485) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/microg protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS. Purity: >98% (SDS-PAGE). Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.
Safety information: 
Hazard information: Non-hazardous
Additional information: 
Synonyms: CHI-MF-120ICAM1-C050; Chimerigen Laboratories