CRF blocking peptide
GTX31922-PEP
Overview
- SupplierGeneTex
- Product NameCRF blocking peptide
- Delivery Days Customer10
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- Concentration200 ug/ml
- Scientific DescriptionCorticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
- Storage Instruction-20°C
- UNSPSC12352202