Cynomolgus PVRIG Protein (Recombinant Human IgG1 Fc, C-terminus) (Thr41-Asp171)

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Product specifications for - Cynomolgus PVRIG Protein (Recombinant Human IgG1 Fc, C-terminus) (Thr41-Asp171)

Overview:
Product group:	Proteins / Signaling Molecule
Category:	Proteins
Subcategory:	Recombinant protein
Target:	PVRIG
Target description:	PVR related immunoglobulin domain containing

Properties:
Purity:	>95%
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352202
Storage instructions:	-20-¦C

Scientific information:
Scientific info:	act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Gene ID:	79037

Scientific information:

Scientific info:

act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Gene ID:

79037

Additional information:
Synonyms:	C7orf15; CD112 receptor; CD112R; nectin-2 receptor; poliovirus receptor related immunoglobulin domain containing; poliovirus receptor-related immunoglobulin domain-containing protein; transmembrane protein PVRIG

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Cynomolgus PVRIG Protein (Recombinant Human IgG1 Fc, C-terminus) (Thr41-Asp171)

Product specifications for - Cynomolgus PVRIG Protein (Recombinant Human IgG1 Fc, C-terminus) (Thr41-Asp171)