Bio-Connect

DR3 peptide

Research Use Only
GTX28443
GeneTex
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    DR3 peptide
  • Delivery Days Customer
    10
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Concentration
    0.20 mg/ml
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202