EBV-EBNA1 1-90 protein

Biorbyt

EBV-EBNA1 1-90 protein

16

Western Blot, ELISA

ELISA, WB

Research Use Only

EBV-EBNA1 Mosaic (residues 1-90, 408-498), S pack protein.This protein does contain a GST-tag.The mosaic protein contains fragments of HHV-4 EBNA1nuclear protein, amino acids: 1-90 and 408-498.The protein is purified by proprietary chromatographictechnique.The Epstein-Barr virus (EBV), a gamma herpesvirus,persists in B lymphocytes for the life of the host.EBNA1 (Epstein-Barr virus nuclear antigen 1) is expressedinfivery form of EBV-related malignancy, includingposttransplant lymphomas. Tumors such as nasopharyngeal cell carcinoma, Hodgkins lymphoma, and Burkittslymphoma (BL) that fail to express some or all of thedominant CD8 T cellscell latent antigens still express EBNA1.A significant proportion of memory CD4 T cellscells thatrecognize lymphoblastoid cell lines (LCLs) are directedagainst the EBNA1 protein.The EBNA1 protein contains a glycine-alanine repeatthat prevents proper processing and presentation throughthe major histocompatibility complex class I (MHC I)pathway

-20°C

12352202