GITR (human):Fc (human) (rec.)

Catalog number: AG-40B-0028-3050
Brand: AdipoGen Life Sciences
Packing: 3 x 50 ug
Other sizes: 50 ug
Price: € 640.00
Expected delivery time: 7 days
Quantity:

Product specifications for - GITR (human):Fc (human) (rec.)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Species: Human
Target: TNFRSF18
Target description: TNF receptor superfamily member 18
Source: 293 Cells
Properties: 
Purity: >95% (SDS-PAGE)
Molecular weight: ~48kDa (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 1 mg/ml
Form supplied: Lyophilized. Contains PBS.
Storage instructions: -20-¦C
Scientific information: 
Scientific info: GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway. - Protein. Human GITR (aa 26-162) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human GITRL. Purity: >95% (SDS-PAGE). GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway.
Gene ID: 8784
Swiss prot ID: Q9Y5U5
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; tumor necrosis factor receptor superfamily member 18