GNE-781 [1936422-33-1]
HY-108696
CAS Number1936422-33-1
Product group Chemicals
Estimated Purity98.19%
Molecular Weight525.59
Overview
- SupplierMedChem Express
- Product NameGNE-781 [1936422-33-1]
- Delivery Days Customer10
- CAS Number1936422-33-1
- CertificationResearch Use Only
- Estimated Purity98.19%
- Molecular FormulaC27H33F2N7O2
- Molecular Weight525.59
- Scientific DescriptionGNE-781 is an orally active, highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. GNE-781 displays antitumor activity in an MOLM-16 AML xenograft model.
- SMILESO=C(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)NC
- Storage Instruction-20°C,-80°C
- UNSPSC12352200