Human AGO2 Partial protein
ORB244993
Overview
- SupplierBiorbyt
- Product NameHuman AGO2 Partial protein
- Delivery Days Customer16
- CertificationResearch Use Only
- Estimated Purity>90%
- Protein IDQ9UKV8
- Protein NameProtein argonaute-2
- Scientific DescriptionAGO2 is required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The minimal RISC appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2.
- Storage Instruction-20°C or -80°C
- UNSPSC12352202