Human APPBP1 protein

GeneTex

Human APPBP1 protein

10

Research Use Only

0.5 mg/ml

NEDD8-activating enzyme E1 regulatory subunit

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimers disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

2°C to 8°C,-20°C

12352202