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GTX68375-pro Image
GTX68375-pro Image
GTX68375-pro Image

Human BRDG1 protein

Research Use Only
GTX68375-PRO
GeneTex
Protein IDQ9ULZ2
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Human BRDG1 protein
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Protein IDQ9ULZ2
  • Protein Name
    Signal-transducing adaptor protein 1
  • Scientific Description
    The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352202