Bio-Connect

Human IL-36 alpha (153a.a.) protein

Research Use Only
ORB107763
Biorbyt
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Human IL-36 alpha (153a.a.) protein
  • Delivery Days Customer
    16
  • Applications Supplier
    HPLC, SDS-PAGE
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases.IL-36C, IL-36F, and IL-36G (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptorfamily members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. Studies showed IL-36C is mainly found in skin and lymphoid tissues, butalso in fetal brain, trachea, stomach and intestine. Notably, IL-36 alpha is the only novel IL-1 family member expressed on Tcells.Recombinant human interleukin-36 alpha (153 a.a.) contains 153 amino acids residues which is a single non-glycosylatedpolypeptide and it shares 57 - 68% a.a. sequence identity with mouse, rabbit, equine and bovine IL-36C and 27 - 57% a.a.sequence identity with other novel IL-1 family members.
  • Source
    E.coli
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352202