Human LRRC32 protein
ORB402990
ApplicationsOther Application
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameHuman LRRC32 protein
- Delivery Days Customer10
- ApplicationsOther Application
- Applications SupplierSDS-PAGE
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionLeucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
- Storage Instruction-20°C
- UNSPSC12352202