Bio-Connect

Human Nectin-2 protein

Research Use Only
ORB348815
Biorbyt
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Human Nectin-2 protein
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202