Human sFasR protein

Biorbyt

Human sFasR protein

16

HPLC, SDS-PAGE

Research Use Only

>95%

Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively.Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases thencleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis byacting as a decoy receptor that serves as a sink for FasL

E.coli

2°C to 8°C,-20°C

12352202