Human Siglec-10 protein
ORB511226
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameHuman Siglec-10 protein
- Delivery Days Customer16
- Applications SupplierSDS-PAGE
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionThe siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
- Storage Instruction-20°C
- UNSPSC12352202