Human UBC7 protein

Biorbyt

Human UBC7 protein

16

HPLC, SDS-PAGE

Research Use Only

>95%

Human Ubquitin Conjugating Enzyme E2 L3 (UBE2L3)/UBCH7 is a class I enzyme which functions in the stress response andthe control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle.UBCH7 mediates the selective degradation of short-lived and abnormal proteins and is highly homologous to UBCH5. It hasbeen demonstrated to participate in the ubiquitinylation of p53, c-Fos and NFkB. UBCH7 is one of two E2s (UBCH5 being theother) with which HECT domain proteins interact with UBCH7 being able to efficiently substitute for UBCH5 in E6-APdependentubiquitinylation.

E.coli

2°C to 8°C,-20°C

12352202