IL-10 (human) (rec.) (His)

Chimerigen Laboratories

IL-10 (human) (rec.) (His)

10

Research Use Only

>95%

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases. - Protein. Human IL-10 (aa 19-178) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: <0.1EU/microg protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS (pH 7.4). Purity: >95% (SDS-PAGE). Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

2°C to 8°C,-20°C

12352202