IL-12, Human(HEK 293-expressed)

Catalog number: Z03023-5
Brand: GenScript
Packing: 5 ug
Other sizes: 25 ug
1 mg
Price: € 128.00
Expected delivery time: 10 days

Product specifications for - IL-12, Human(HEK 293-expressed)

Product group: Proteins / Signaling Molecule
Category: Chemokines / cytokines
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Storage instructions: Lyophilized recombinant Human Interleukin 12(IL-12) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rh-IL12 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Scientific information: 
Scientific info: Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has been shown to have extensive amino acid sequence homology to the extracellular domain of the human IL-6 receptor while the p35 subunit shows distant but significant sequence similarity to IL-6, G-CSF, and chicken MGF. These observations have led to the suggestion that IL-12 might have evolved from a cytokine/soluble receptor complex. Human and mouse IL-12 share 70% and 60% amino acid sequence homology in their p40 and p35 subunits, respectively. IL-12 apparently shows species specificity with human IL-12 reportedly showing minimal activity in the mouse system.
Additional information: 
Synonyms: Z03023-5; GenScript