IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)

Catalog number: CHI-MF-12002-C010
Brand: Chimerigen Laboratories
Packing: 10 ug
Other sizes: 50 ug
5 x 10 ug
Price: € 195.00
Expected delivery time: 7 days

Product specifications for - IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)

Product group: Proteins / Signaling Molecule
Category: Chemokines / cytokines
Species: Mouse
Source: NS1 cells
Purity: >98% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116127
Form supplied: Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
Swiss prot ID: NP_032392.1
Additional information: 
Synonyms: CHI-MF-12002-C010; Chimerigen Laboratories; IL2; lymphokine; TCGF; IL-2; involved in regulation of T-cell clonal expansion; interleukin-2; aldesleukin; T cell growth factor; interleukin 2
Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation: X.X. Zheng, et al.; J. Immunol. 154, 5590 (1995) Read more
Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration: D.H. Barouch, et al.; J. Immunol. 161, 1875 (1998) Read more
IL-2 receptor-targeted cytolytic IL-2/Fc fusion protein treatment blocks diabetogenic autoimmunity in nonobese diabetic mice: X.X. Zheng, et al.; J. Immunol. 163, 4041 (1999) Read more
Effects of Cyclosporine on Transplant Tolerance: The Role of IL-2: X.X. Zheng, et al.; Am. J. Transplant. 7, 1907 (2007) Read more
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response: O. Feinerman, et al.; Mol. Sys. Biol. 6, 437 (2010) Read more